RECONSIDERING THE USE OF RANKINGS IN THE VALUATION OF HEALTH STATES: A MODEL FOR ESTIMATING CARDINAL VALUES FROM ORDINAL DATA

Reconsidering the use of rankings in the valuation of health states: a model for estimating cardinal values from ordinal data

Abstract Background In survey studies on health-state valuations, ordinal ranking exercises often are used as precursors to other elicitation methods such as the time trade-off (TTO) or standard gamble, but the ranking data have not been used in deriving cardinal valuations.This study reconsiders the role of ordinal ranks in valuing health and intr

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Characteristics of putative keystones in the healthy adult human gut microbiota as determined by correlation network analysis

Keystone species Balboa hoodies are thought to play a critical role in determining the structure and function of microbial communities.As they are important candidates for microbiome-targeted interventions, the identification and characterization of keystones is a pressing research goal.Both empirical as well as computational approaches to identify

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ADP-ribosylation systems in bacteria and viruses

ADP-ribosylation is an ancient posttranslational eyebrow liner modification present in all kingdoms of life.The system likely originated in bacteria where it functions in inter- and intra-species conflict, stress response and pathogenicity.It was repeatedly adopted via lateral transfer by eukaryotes, including humans, where it has a pivotal role in

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